Recently, a certain virus has the scientific community in an
uproar. The culprit, H5N1, is the virus that causes the bird flu. H5N1 is usually only transferred from birds to humans, but two teams of researchers decided to try and manipulate the virus so that it could theoretically be transferred from human to human.
The task turned out to be pretty simple, with only four mutations required to make the virus spreadable between ferrets (a commonly-used model for humans). The whole controversy arose when the researchers tried to submit their findings for publication. When it heard wind of the studies, the U.S. government became concerned that bio-terrorists could use the information to threaten public safety.
After much
debate and deliberation, the National Science Advisory Board for Biosecurity, supported by the government, recommended that the articles be published without the important methods and data. Last week,
Nature decided to publish one of the articles independently of the board's decision.
While the research community primarily deals with pathological viruses like H5N1, popular culture has come up with several additional uses for the microorganisms. In fact, alternative uses for viruses are very prevalent in mainstream media and the entrainment industry. The question is, are the references based in science?
Computer viruses
Although the metaphor can only stretch so far, it seems that computer viruses are
aptly named. Biological
viruses are small pieces of DNA or RNA that are injected into living cells, while computer
viruses are small pieces of software that latch onto an existing program or document. But both kinds of viruses lack the ability to replicate themselves, so they use their hosts' resources to replicate, spread, and cause harm to the host from the inside.
One important
difference between biological and computer viruses is that computer viruses are man-made while biological viruses come about through natural selection. This means that biological viruses (like the bird flu virus) undergo mutations, while a computer virus code stays the same as it is passed between computers.
Continuous advances in technology might facilitate
interactions between computer viruses and the human body. If implanted electronic devices, like pacemakers, were "infected" with computer viruses, the devices could cause harm to the people who have them.
Photo from I Can Has Cheezburger? Internet ideas "going viral"The term "viral" actually came from another term commonly seen on the internet: "meme." When you see this term, you might think of internet memes like
LOLcats,
Philosoraptor, or Condescending
Wonka. But actually there's a more general definition.
Essentially, theorists say that a
meme is the most basic unit of culture. If you were to dissect culture down to its fundamental building blocks, you would find that its made up of many small ideas, which are called memes.
A theory called memetics came up when researchers decided to study the evolution of memes--or how memes behave like genes. Memes are spread from brain to brain in the same way DNA is spread by viruses. Like viral DNA, memes also change and evolve as they propagate, and if they don't keep spreading they might die. However, memetics has been contested by some who think the meme can't be categorized, and by some who say it deviates from the original idea of the meme.
Viruses in the moviesBasically, movies about viruses portray exactly what challengers to the bird flu article publications are afraid of.
Movies like
I am Legend,
28 Days Later, and
Contagion, show what might happen if enemies used a viral plague to take over the world. Possibly because this catastrophe has never actually happened, movie-goers seem to be absolutely fascinated by the idea.
The most recent virus-related movie,
Contagion, seems to have a firm
basis in science. In an
interview with
io9, the movie's screenwriter, Scott Z. Burns, tells how he relied heavily on input from virologist and epidemiologists from the Center for Disease Control. Some scenes in the movies were even shot at the CDC's facility.
In fact, the CDC seems to be doing everything it can to increase its popular appeal. Last year, a CDC blogger wrote a
post about how to survive a zombie apocalypse. And actually, as the article suggests, a zombie attack bears a lot of resemblance to a virus outbreak.
So I would suggest reading up on the CDC's helpful tips, just in case we are overridden by zombies or (God forbid) virulent ferrets.